Christopher Cottrell Receives Ruth L Kirschstein Predoctoral Fellowship

Christopher Cottrell, a graduate student in Andrew Ward's laboratory, has been awarded a Ruth L. Kirschstein predoctoral fellowship from the National Institutes of Health. This program allows for promising students with potential to develop into a productive, independent research scientists, to obtain mentored research training while conducting dissertation research.

Cottrell's project seeks to broaden autologous Tier 2 neutralizing antibodies by both increasing the level of somatic hypermutation and directing somatic hypermutation toward specific neutralizing epitopes of the HIV envelope. His work will focus on broadening the specificity of vaccine elicited autologous neutralizing antibodies via iterative structure-based design of immunogens; increasing the level of somatic hypermutation by prolonging the duration of germinal center reactions using continuous antigen delivery; and improving trafficking of immunogens to follicular dendritic cells.

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The Scripps Research Institute