Publications

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2018
Dosenovic P, Kara EE, Pettersson A-K, McGuire AT, Gray M, Hartweger H, Thientosapol ES, Stamatatos L, Nussenzweig MC.  2018.  Anti-HIV-1 B cell responses are dependent on B cell precursor frequency and antigen-binding affinity.. Proc Natl Acad Sci U S A. 115(18):4743-4748.
Cohn LB, da Silva IT, Valieris R, Huang AS, Lorenzi JCC, Cohen YZ, Pai JA, Butler AL, Caskey M, Jankovic M et al..  2018.  Clonal CD4 T cells in the HIV-1 latent reservoir display a distinct gene profile upon reactivation.. Nat Med. 24(5):604-609.
Rantalainen K, Berndsen ZT, Murrell S, Cao L, Omorodion O, Torres JL, Wu M, Umotoy J, Copps J, Poignard P et al..  2018.  Co-evolution of HIV Envelope and Apex-Targeting Neutralizing Antibody Lineage Provides Benchmarks for Vaccine Design.. Cell Rep. 23(11):3249-3261.
Malherbe DC, Mendy J, Vang L, Barnette PT, Reed J, Lakhashe SK, Owuor J, Gach JS, Legasse AW, Axthelm MK et al..  2018.  Combination Adenovirus and Protein Vaccines Prevent Infection or Reduce Viral Burden after Heterologous Clade C Simian-Human Immunodeficiency Virus Mucosal Challenge.. J Virol. 92(2)
Mendoza P, Gruell H, Nogueira L, Pai JA, Butler AL, Millard K, Lehmann C, Suárez I, Oliveira TY, Lorenzi JCC et al..  2018.  Combination therapy with anti-HIV-1 antibodies maintains viral suppression.. Nature. 561(7724):479-484.
Liu W, Wong YChun, M Y Chen S, Tang J, Wang H, Cheung AKa Loon, Chen Z.  2018.  DNA prime/MVTT boost regimen with HIV-1 mosaic Gag enhances the potency of antigen-specific immune responses.. Vaccine. 36(31):4621-4632.
Schwartz EJ, Vaidya NK, Dorman KS, Carpenter S, Mealey RH.  2018.  Dynamics of lentiviral infection in vivo in the absence of adaptive immune responses.. Virology. 513:108-113.
Prévost J, Richard J, Ding S, Pacheco B, Charlebois R, Hahn BH, Kaufmann DE, Finzi A.  2018.  Envelope glycoproteins sampling states 2/3 are susceptible to ADCC by sera from HIV-1-infected individuals.. Virology. 515:38-45.
Klasse PJ, Ketas TJ, Cottrell CA, Ozorowski G, Debnath G, Camara D, Francomano E, Pugach P, Ringe RP, Labranche CC et al..  2018.  Epitopes for neutralizing antibodies induced by HIV-1 envelope glycoprotein BG505 SOSIP trimers in rabbits and macaques.. PLoS Pathog. 14(2):e1006913.
Martinot AJ, Abbink P, Afacan O, Prohl AK, Bronson R, Hecht JL, Borducchi EN, Larocca RA, Peterson RL, Rinaldi W et al..  2018.  Fetal Neuropathology in Zika Virus-Infected Pregnant Female Rhesus Monkeys.. Cell. 173(5):1111-1122.e10.
Cheng HD, Grimm SK, Gilman MSa, Gwom LChristian, Sok D, Sundling C, Donofrio G, Karlsson Hedestam GB, Bonsignori M, Haynes BF et al..  2018.  Fine epitope signature of antibody neutralization breadth at the HIV-1 envelope CD4-binding site.. JCI Insight. 3(5)
Cao L, Diedrich JK, Ma Y, Wang N, Pauthner M, Park S-KRobin, Delahunty CM, McLellan JS, Burton DR, Yates JR et al..  2018.  Global site-specific analysis of glycoprotein N-glycan processing.. Nat Protoc. 13(6):1196-1212.
Allen JD, Sanders RW, Doores KJ, Crispin M.  2018.  Harnessing post-translational modifications for next-generation HIV immunogens.. Biochem Soc Trans. 46(3):691-698.
Porichis F, Hart MG, Massa A, Everett HL, Morou A, Richard J, Brassard N, Veillette M, Hassan M, Le Ly N et al..  2018.  Immune Checkpoint Blockade Restores HIV-Specific CD4 T Cell Help for NK Cells.. J Immunol. 201(3):971-981.
Gaya M, Barral P, Burbage M, Aggarwal S, Montaner B, Navia AWarren, Aid M, Tsui C, Maldonado P, Nair U et al..  2018.  Initiation of Antiviral B Cell Immunity Relies on Innate Signals from Spatially Positioned NKT Cells.. Cell. 172(3):517-533.e20.
Behrens A-J, Kumar A, Medina-Ramírez M, Cupo A, Marshall K, Portillo VMCruz, Harvey DJ, Ozorowski G, Zitzmann N, Wilson IA et al..  2018.  Integrity of Glycosylation Processing of a Glycan-Depleted Trimeric HIV-1 Immunogen Targeting Key B-Cell Lineages.. J Proteome Res. 17(3):987-999.
Harvey DJ, Seabright GE, Vasiljevic S, Crispin M, Struwe WB.  2018.  Isomer Information from Ion Mobility Separation of High-Mannose Glycan Fragments.. J Am Soc Mass Spectrom. 29(5):972-988.
Cohen YZ, Lorenzi JCC, Seaman MS, Nogueira L, Schoofs T, Krassnig L, Butler A, Millard K, Fitzsimons T, Daniell X et al..  2018.  Neutralizing Activity of Broadly Neutralizing Anti-HIV-1 Antibodies against Clade B Clinical Isolates Produced in Peripheral Blood Mononuclear Cells.. J Virol. 92(5)
Walker LM, Burton DR.  2018.  Passive immunotherapy of viral infections: 'super-antibodies' enter the fray.. Nat Rev Immunol. 18(5):297-308.
Abbott RK, Lee J H, Menis S, Skog P, Rossi M, Ota T, Kulp DW, Bhullar D, Kalyuzhniy O, Havenar-Daughton C et al..  2018.  Precursor Frequency and Affinity Determine B Cell Competitive Fitness in Germinal Centers, Tested with Germline-Targeting HIV Vaccine Immunogens.. Immunity. 48(1):133-146.e6.
Tsui C, Martinez-Martin N, Gaya M, Maldonado P, Llorian M, Legrave NM, Rossi M, MacRae JI, Cameron AJ, Parker PJ et al..  2018.  Protein Kinase C-β Dictates B Cell Fate by Regulating Mitochondrial Remodeling, Metabolic Reprogramming, and Heme Biosynthesis.. Immunity. 48(6):1144-1159.e5.
Saha JMd, Liu H, Hu P-W, Nikolai BC, Wu H, Miao H, Rice AP.  2018.  Proteomic Profiling of a Primary CD4 T Cell Model of HIV-1 Latency Identifies Proteins Whose Differential Expression Correlates with Reactivation of Latent HIV-1.. AIDS Res Hum Retroviruses. 34(1):103-110.
Cohen YZ, Lorenzi JCC, Krassnig L, Barton JP, Burke L, Pai J, Lu C-L, Mendoza P, Oliveira TY, Sleckman C et al..  2018.  Relationship between latent and rebound viruses in a clinical trial of anti-HIV-1 antibody 3BNC117.. J Exp Med. 215(9):2311-2324.
Watanabe Y, Vasiljevic S, Allen JD, Seabright GE, Duyvesteyn HME, Doores KJ, Crispin M, Struwe WB.  2018.  Signature of Antibody Domain Exchange by Native Mass Spectrometry and Collision-Induced Unfolding.. Anal Chem. 90(12):7325-7331.
Gautam R, Nishimura Y, Gaughan N, Gazumyan A, Schoofs T, Buckler-White A, Seaman MS, Swihart BJ, Follmann DA, Nussenzweig MC et al..  2018.  A single injection of crystallizable fragment domain-modified antibodies elicits durable protection from SHIV infection.. Nat Med. 24(5):610-616.

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