HIV Broadly Neutralizing Antibodies: Taking Good Care Of The 98.

TitleHIV Broadly Neutralizing Antibodies: Taking Good Care Of The 98.
Publication TypeJournal Article
Year of Publication2016
AuthorsSok D, Burton DR
JournalImmunity
Volume45
Issue5
Pagination958-960
Date Published11/15/2016
ISSN1097-4180
Abstract

In this issue of Immunity, Huang et al. (2016) describe an exceptionally broad and potent neutralizing antibody to HIV. This antibody, N6, is capable of neutralizing up to 98% of global isolates with a potent median IC50 of 0.04 μg/mL, making it the current "best-in-class" for bNAbs targeting the CD4 binding site.

DOI10.1016/j.immuni.2016.10.033
Alternate JournalImmunity
PubMed ID27851923
Grant ListUM1 AI100663 / AI / NIAID NIH HHS / United States
CHAVI-ID: 
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