IRIS: the unfortunate rainbow of HIV.

TitleIRIS: the unfortunate rainbow of HIV.
Publication TypeJournal Article
Year of Publication2012
AuthorsChahroudi A, Silvestri G
JournalBlood
Volume119
Issue13
Pagination2971-2
Date Published2012 Mar 29
ISSN1528-0020
KeywordsCD4-Positive T-Lymphocytes, Cell Proliferation, Female, HIV Infections, HIV-1, Humans, Immune Reconstitution Inflammatory Syndrome, Male
Abstract

In this issue of Blood, Mahnke and colleagues identify polyfunctional CD4(+) T-cell responses directed against specific opportunistic pathogens in HIV-infected patients who develop immune reconstitution inflammatory syndrome (IRIS) after initiation of antiretroviral therapy (ART). This work provides a mechanistic advance to our understanding of IRIS pathogenesis.

DOI10.1182/blood-2012-01-403683
Alternate JournalBlood
PubMed ID22461468