Unraveling the web of viroinformatics: computational tools and databases in viral research.

TitleUnraveling the web of viroinformatics: computational tools and databases in viral research.
Publication TypeJournal Article
Year of Publication2014
AuthorsSharma D, Priyadarshini P, Vrati S
JournalJ Virol
Date Published2014 Nov 26
ISSN1098-5514
Abstract

The beginning of the second century of research in the field of virology (the first virus was discovered in 1898) was marked with its amalgamation with bioinformatics resulting in the birth of a new domain - viroinformatics. The availability of more than 100 web servers and databases embracing all or specific viruses (for example dengue, influenza, hepatitis, HIV, HFV, HPV, West Nile etc.) as well as distinct applications (comparative/diversity analysis, viral recombination, siRNA/shRNA/miRNA studies, RNA folding, protein-protein interaction, structural analysis, phylotyping/genotyping) will definitely aid the development of effective drugs and vaccines. However, the information about their access and utility is not available at any single source/platform. Therefore, a compendium of various computational tools/resources dedicated specifically to virology is presented in this article.

DOI10.1128/JVI.02027-14
Alternate JournalJ. Virol.
PubMed ID25428870
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