Publications

Richard J, Prévost J, von Bredow B, Ding S, Brassard N, Medjahed H, Coutu M, Melillo B, Bibollet-Ruche F, Hahn BH et al..  2017.  BST-2 Expression Modulates Small CD4 Mimetic Sensitization of HIV-1-infected cells to ADCC.. J Virol. 91(11):pii:e00219-17.

Martin-Gayo E, Cronin J, Hickman T, Ouyang Z, Lindqvist M, Kolb KE, Wiesch JSchulze Zu, Cubas R, Porichis F, Shalek AK et al..  2017.  Circulating CXCR5(+)CXCR3(+)PD-1(lo) Tfh-like cells in HIV-1 controllers with neutralizing antibody breadth.. JCI Insight. 2(2):e89574.

Alsahafi N, Richard J, Prévost J, Coutu M, Brassard N, Parsons MS, Kaufmann DE, Brockman M, Finzi A.  2017.  Impaired Downregulation of NKG2D Ligands by Nef Proteins from Elite Controllers Sensitizes HIV-1-Infected Cells to Antibody-Dependent Cellular Cytotoxicity.. J Virol. 91(16):pii:e00109-17.

Prévost J, Zoubchenok D, Richard J, Veillette M, Pacheco B, Coutu M, Brassard N, Parsons MS, Ruxrungtham K, Bunupuradah T et al..  2017.  Influence of the Envelope gp120 Phe 43 Cavity on HIV-1 Sensitivity to Antibody-Dependent Cell-Mediated Cytotoxicity Responses.. J Virol. 91(7):pii:e02452-16.

Ranasinghe S, Lamothe PA, Soghoian DZ, Kazer SW, Cole MB, Shalek AK, Yosef N, R Jones B, Donaghey F, Nwonu C et al..  2016.  Antiviral CD8(+) T Cells Restricted by Human Leukocyte Antigen Class II Exist during Natural HIV Infection and Exhibit Clonal Expansion.. Immunity. 45(4):917-930.

Havenar-Daughton C, Lindqvist M, Heit A, Wu JE, Reiss SM, Kendric K, Bélanger S, Kasturi SPai, Landais E, Akondy RS et al..  2016.  CXCL13 is a plasma biomarker of germinal center activity.. Proc Natl Acad Sci U S A.

Baxter AE, Niessl J, Fromentin R, Richard J, Porichis F, Charlebois R, Massanella M, Brassard N, Alsahafi N, Delgado G-G et al..  2016.  Single-Cell Characterization of Viral Translation-Competent Reservoirs in HIV-Infected Individuals.. Cell Host Microbe. 20(3):368-80.

Lee WShi, Richard J, Lichtfuss M, Smith AB, Park J, Courter JR, Melillo BN, Sodroski JG, Kaufmann DE, Finzi A et al..  2015.  Antibody-Dependent Cellular Cytotoxicity against Reactivated HIV-1-Infected Cells.. J Virol. 90(4):2021-30.

Richard J, Veillette M, Brassard N, Iyer SS, Roger M, Martin L, Pazgier M, Schön A, Freire E, Routy J-P et al..  2015.  CD4 mimetics sensitize HIV-1-infected cells to ADCC.. Proc Natl Acad Sci U S A. 112(20):E2687-94.

Heesters BA, Lindqvist M, Vagefi PA, Scully EP, Schildberg FA, Altfeld M, Walker BD, Kaufmann DE, Carroll MC.  2015.  Follicular Dendritic Cells Retain Infectious HIV in Cycling Endosomes.. PLoS Pathog. 11(12):e1005285.

Ranasinghe S, Soghoian DZ, Lindqvist M, Ghebremichael M, Donaghey F, Carrington M, Seaman MS, Kaufmann DE, Walker BD, Porichis F.  2015.  HIV-1 antibody neutralization breadth is associated with enhanced HIV-specific CD4+ T cell responses.. J Virol.

Alsahafi N, Ding S, Richard J, Markle T, Brassard N, Walker B, Lewis GK, Kaufmann DE, Brockman MA, Finzi A.  2015.  Nef Proteins from HIV-1 Elite Controllers Are Inefficient at Preventing Antibody-Dependent Cellular Cytotoxicity.. J Virol. 90(6):2993-3002.

Richard J, Veillette M, Ding S, Zoubchenok D, Alsahafi N, Coutu M, Brassard N, Park J, Courter JR, Melillo B et al..  2015.  Small CD4 Mimetics Prevent HIV-1 Uninfected Bystander CD4 + T Cell Killing Mediated by Antibody-dependent Cell-mediated Cytotoxicity.. EBioMedicine. 3:122-34.

Porichis F, Hart MG, Zupkosky J, Barblu L, Kwon DS, McMullen A, Brennan T, Ahmed R, Freeman GJ, Kavanagh DG et al..  2014.  Differential impact of PD-1 and/or IL-10 blockade on HIV-1-specific CD4 T cell and antigen-presenting cell functions.. J Virol.

Morou A, Palmer BE, Kaufmann DE.  2014.  Distinctive features of CD4+ T cell dysfunction in chronic viral infections.. Curr Opin HIV AIDS. 9(5):446-51.

Seddiki N, Kaufmann DE.  2014.  Editorial overview: cell dysfunction and exhaustion in HIV infection.. Curr Opin HIV AIDS. 9(5):437-8.

Porichis F, Hart MG, Griesbeck M, Everett HL, Hassan M, Baxter AE, Lindqvist M, Miller SM, Soghoian DZ, Kavanagh DG et al..  2014.  High-throughput detection of miRNAs and gene-specific mRNA at the single-cell level by flow cytometry.. Nat Commun. 5:5641.

Porichis F, Hart MG, Zupkosky J, Barblu L, Kaufmann DE.  2013.  In vitro assay to evaluate the impact of immunoregulatory pathways on HIV-specific CD4 T cell effector function.. J Vis Exp. (80):e50821.

Burton DR, Ahmed R, Barouch DH, Butera ST, Crotty S, Godzik A, Kaufmann DE, McElrath JM, Nussenzweig MC, Pulendran B et al..  2012.  A Blueprint for HIV Vaccine Discovery.. Cell Host Microbe. 12(4):396-407.

Kwon DS, Angin M, Hongo TC, Law KM, Johnson J, Porichis F, Hart MG, Pavlik DF, Tighe DP, Kavanagh DG et al..  2012.  CD4+ CD25+ regulatory T cells impair HIV-1-specific CD4 T cell responses by upregulating interleukin-10 production in monocytes.. J Virol. 86(12):6586-94.

Angin M, Kwon DS, Streeck H, Wen F, King M, Rezai A, Law KM, Hongo TC, Pyo A, Piechocka-Trocha A et al..  2012.  Preserved function of regulatory T cells in chronic HIV-1 infection despite decreased numbers in blood and tissue.. J Infect Dis. 205(10):1495-500.

Porichis F, Kaufmann DE.  2012.  Role of PD-1 in HIV pathogenesis and as target for therapy.. Curr HIV/AIDS Rep. 9(1):81-90.

Chen H, Ndhlovu ZM, Liu D, Porter LC, Fang JW, Darko S, Brockman MA, Miura T, Brumme ZL, Schneidewind A et al..  2012.  TCR clonotypes modulate the protective effect of HLA class I molecules in HIV-1 infection.. Nat Immunol. 13(7):691-700.