Publications

Prévost J, Richard J, Ding S, Pacheco B, Charlebois R, Hahn BH, Kaufmann DE, Finzi A.  2018.  Envelope glycoproteins sampling states 2/3 are susceptible to ADCC by sera from HIV-1-infected individuals.. Virology. 515:38-45.

Porichis F, Hart MG, Massa A, Everett HL, Morou A, Richard J, Brassard N, Veillette M, Hassan M, Le Ly N et al..  2018.  Immune Checkpoint Blockade Restores HIV-Specific CD4 T Cell Help for NK Cells.. J Immunol. 201(3):971-981.

Niessl J, Baxter AE, Kaufmann DE.  2018.  Tools for Visualizing HIV in Cure Research.. Curr HIV/AIDS Rep.

Richard J, Prévost J, Baxter AE, von Bredow B, Ding S, Medjahed H, Delgado GG, Brassard N, Stürzel CM, Kirchhoff F et al..  2018.  Uninfected Bystander Cells Impact the Measurement of HIV-Specific Antibody-Dependent Cellular Cytotoxicity Responses.. MBio. 9(2)

Richard J, Prévost J, von Bredow B, Ding S, Brassard N, Medjahed H, Coutu M, Melillo B, Bibollet-Ruche F, Hahn BH et al..  2017.  BST-2 Expression Modulates Small CD4 Mimetic Sensitization of HIV-1-infected cells to ADCC.. J Virol. 91(11):pii:e00219-17.

Martin-Gayo E, Cronin J, Hickman T, Ouyang Z, Lindqvist M, Kolb KE, Wiesch JSchulze Zu, Cubas R, Porichis F, Shalek AK et al..  2017.  Circulating CXCR5(+)CXCR3(+)PD-1(lo) Tfh-like cells in HIV-1 controllers with neutralizing antibody breadth.. JCI Insight. 2(2):e89574.

Reiss S, Baxter AE, Cirelli KM, Dan JM, Morou A, Daigneault A, Brassard N, Silvestri G, Routy J-P, Havenar-Daughton C et al..  2017.  Comparative analysis of activation induced marker (AIM) assays for sensitive identification of antigen-specific CD4 T cells.. PLoS One. 12(10):e0186998.

Alsahafi N, Richard J, Prévost J, Coutu M, Brassard N, Parsons MS, Kaufmann DE, Brockman M, Finzi A.  2017.  Impaired Downregulation of NKG2D Ligands by Nef Proteins from Elite Controllers Sensitizes HIV-1-Infected Cells to Antibody-Dependent Cellular Cytotoxicity.. J Virol. 91(16):pii:e00109-17.

Prévost J, Zoubchenok D, Richard J, Veillette M, Pacheco B, Coutu M, Brassard N, Parsons MS, Ruxrungtham K, Bunupuradah T et al..  2017.  Influence of the Envelope gp120 Phe 43 Cavity on HIV-1 Sensitivity to Antibody-Dependent Cell-Mediated Cytotoxicity Responses.. J Virol. 91(7)

Baxter AE, Niessl J, Fromentin R, Richard J, Porichis F, Massanella M, Brassard N, Alsahafi N, Routy J-P, Finzi A et al..  2017.  Multiparametric characterization of rare HIV-infected cells using an RNA-flow FISH technique.. Nat Protoc. 12(10):2029-2049.

Baxter AE, Niessl J, Morou A, Kaufmann DE.  2017.  RNA flow cytometric FISH for investigations into HIV immunology, vaccination and cure strategies.. AIDS Res Ther. 14(1):40.

Ranasinghe S, Lamothe PA, Soghoian DZ, Kazer SW, Cole MB, Shalek AK, Yosef N, R Jones B, Donaghey F, Nwonu C et al..  2016.  Antiviral CD8(+) T Cells Restricted by Human Leukocyte Antigen Class II Exist during Natural HIV Infection and Exhibit Clonal Expansion.. Immunity. 45(4):917-930.

Havenar-Daughton C, Lindqvist M, Heit A, Wu JE, Reiss SM, Kendric K, Bélanger S, Kasturi SPai, Landais E, Akondy RS et al..  2016.  CXCL13 is a plasma biomarker of germinal center activity.. Proc Natl Acad Sci U S A.

Baxter AE, Niessl J, Fromentin R, Richard J, Porichis F, Charlebois R, Massanella M, Brassard N, Alsahafi N, Delgado G-G et al..  2016.  Single-Cell Characterization of Viral Translation-Competent Reservoirs in HIV-Infected Individuals.. Cell Host Microbe. 20(3):368-80.

Lee WShi, Richard J, Lichtfuss M, Smith AB, Park J, Courter JR, Melillo BN, Sodroski JG, Kaufmann DE, Finzi A et al..  2015.  Antibody-Dependent Cellular Cytotoxicity against Reactivated HIV-1-Infected Cells.. J Virol. 90(4):2021-30.

Richard J, Veillette M, Brassard N, Iyer SS, Roger M, Martin L, Pazgier M, Schön A, Freire E, Routy J-P et al..  2015.  CD4 mimetics sensitize HIV-1-infected cells to ADCC.. Proc Natl Acad Sci U S A. 112(20):E2687-94.

Heesters BA, Lindqvist M, Vagefi PA, Scully EP, Schildberg FA, Altfeld M, Walker BD, Kaufmann DE, Carroll MC.  2015.  Follicular Dendritic Cells Retain Infectious HIV in Cycling Endosomes.. PLoS Pathog. 11(12):e1005285.

Ranasinghe S, Soghoian DZ, Lindqvist M, Ghebremichael M, Donaghey F, Carrington M, Seaman MS, Kaufmann DE, Walker BD, Porichis F.  2015.  HIV-1 antibody neutralization breadth is associated with enhanced HIV-specific CD4+ T cell responses.. J Virol.

Alsahafi N, Ding S, Richard J, Markle T, Brassard N, Walker B, Lewis GK, Kaufmann DE, Brockman MA, Finzi A.  2015.  Nef Proteins from HIV-1 Elite Controllers Are Inefficient at Preventing Antibody-Dependent Cellular Cytotoxicity.. J Virol. 90(6):2993-3002.

Richard J, Veillette M, Ding S, Zoubchenok D, Alsahafi N, Coutu M, Brassard N, Park J, Courter JR, Melillo B et al..  2015.  Small CD4 Mimetics Prevent HIV-1 Uninfected Bystander CD4 + T Cell Killing Mediated by Antibody-dependent Cell-mediated Cytotoxicity.. EBioMedicine. 3:122-34.

Porichis F, Hart MG, Zupkosky J, Barblu L, Kwon DS, McMullen A, Brennan T, Ahmed R, Freeman GJ, Kavanagh DG et al..  2014.  Differential impact of PD-1 and/or IL-10 blockade on HIV-1-specific CD4 T cell and antigen-presenting cell functions.. J Virol.

Morou A, Palmer BE, Kaufmann DE.  2014.  Distinctive features of CD4+ T cell dysfunction in chronic viral infections.. Curr Opin HIV AIDS. 9(5):446-51.

Seddiki N, Kaufmann DE.  2014.  Editorial overview: cell dysfunction and exhaustion in HIV infection.. Curr Opin HIV AIDS. 9(5):437-8.

Porichis F, Hart MG, Griesbeck M, Everett HL, Hassan M, Baxter AE, Lindqvist M, Miller SM, Soghoian DZ, Kavanagh DG et al..  2014.  High-throughput detection of miRNAs and gene-specific mRNA at the single-cell level by flow cytometry.. Nat Commun. 5:5641.

Porichis F, Hart MG, Zupkosky J, Barblu L, Kaufmann DE.  2013.  In vitro assay to evaluate the impact of immunoregulatory pathways on HIV-specific CD4 T cell effector function.. J Vis Exp. (80):e50821.