Publications

Found 68 results
Filters: Author is Wilson, Ian A  [Clear All Filters]
2016
Behrens A-J, Vasiljevic S, Pritchard LK, Harvey DJ, Andev RS, Krumm SA, Struwe WB, Cupo A, Kumar A, Zitzmann N et al..  2016.  Composition and Antigenic Effects of Individual Glycan Sites of a Trimeric HIV-1 Envelope Glycoprotein.. Cell Rep.
Irimia A, Sarkar A, Stanfield RL, Wilson IA.  2016.  Crystallographic Identification of Lipid as an Integral Component of the Epitope of HIV Broadly Neutralizing Antibody 4E10.. Immunity. 44(1):21-31.
MacLeod DT, Choi NM, Briney B, Garces F, Ver LS, Landais E, Murrell B, Wrin T, Kilembe W, Liang C-H et al..  2016.  Early Antibody Lineage Diversification and Independent Limb Maturation Lead to Broad HIV-1 Neutralization Targeting the Env High-Mannose Patch.. Immunity. 44(5):1215-26.
Steichen JM, Kulp DW, Tokatlian T, Escolano A, Dosenovic P, Stanfield RL, McCoy LE, Ozorowski G, Hu X, Kalyuzhniy O et al..  2016.  HIV Vaccine Design to Target Germline Precursors of Glycan-Dependent Broadly Neutralizing Antibodies.. Immunity.
van Gils MJ, van den Kerkhof TLGM, Ozorowski G, Cottrell CA, Sok D, Pauthner M, Pallesen J, de Val N, Yasmeen A, de Taeye SW et al..  2016.  An HIV-1 antibody from an elite neutralizer implicates the fusion peptide as a site of vulnerability.. Nat Microbiol. 2:16199.
Jardine JG, Kulp DW, Havenar-Daughton C, Sarkar A, Briney B, Sok D, Sesterhenn F, Ereño-Orbea J, Kalyuzhniy O, Deresa I et al..  2016.  HIV-1 broadly neutralizing antibody precursor B cells revealed by germline-targeting immunogen.. Science. 351(6280):1458-63.
McCoy LE, van Gils MJ, Ozorowski G, Messmer T, Briney B, Voss JE, Kulp DW, Macauley MS, Sok D, Pauthner M et al..  2016.  Holes in the Glycan Shield of the Native HIV Envelope Are a Target of Trimer-Elicited Neutralizing Antibodies.. Cell Rep. 16(9):2327-38.
Kong L, Ju B, Chen Y, He L, Ren L, Liu J, Hong K, Su B, Wang Z, Ozorowski G et al..  2016.  Key gp120 Glycans Pose Roadblocks to the Rapid Development of VRC01-Class Antibodies in an HIV-1-Infected Chinese Donor.. Immunity. 44(4):939-50.
Jardine JG, Sok D, Julien J-P, Briney B, Sarkar A, Liang C-H, Scherer EA, Dunand CJHenry, Adachi Y, Diwanji D et al..  2016.  Minimally Mutated HIV-1 Broadly Neutralizing Antibodies to Guide Reductionist Vaccine Design.. PLoS Pathog. 12(8):e1005815.
He L, de Val N, Morris CD, Vora N, Thinnes TC, Kong L, Azadnia P, Sok D, Zhou B, Burton DR et al..  2016.  Presenting native-like trimeric HIV-1 antigens with self-assembling nanoparticles.. Nat Commun. 7:12041.
Sok D, Pauthner M, Briney B, Lee J H, Saye-Francisco KL, Hsueh J, Ramos A, Le KM, Jones M, Jardine JG et al..  2016.  A Prominent Site of Antibody Vulnerability on HIV Envelope Incorporates a Motif Associated with CCR5 Binding and Its Camouflaging Glycans.. Immunity. 45(1):31-45.
Klasse PJ, Labranche CC, Ketas TJ, Ozorowski G, Cupo A, Pugach P, Ringe RP, Golabek M, van Gils MJ, Guttman M et al..  2016.  Sequential and Simultaneous Immunization of Rabbits with HIV-1 Envelope Glycoprotein SOSIP.664 Trimers from Clades A, B and C.. PLoS Pathog. 12(9):e1005864.
Briney B, Sok D, Jardine JG, Kulp DW, Skog P, Menis S, Jacak R, Kalyuzhniy O, de Val N, Sesterhenn F et al..  2016.  Tailored Immunogens Direct Affinity Maturation toward HIV Neutralizing Antibodies.. Cell. 166(6):1459-1470.e11.
Kong L, He L, de Val N, Vora N, Morris CD, Azadnia P, Sok D, Zhou B, Burton DR, Ward AB et al..  2016.  Uncleaved prefusion-optimized gp140 trimers derived from analysis of HIV-1 envelope metastability.. Nat Commun. 7:12040.
2015
Garces F, Lee J H, de Val N, de la Peña ATorrents, Kong L, Puchades C, Hua Y, Stanfield RL, Burton DR, Moore JP et al..  2015.  Affinity Maturation of a Potent Family of HIV Antibodies Is Primarily Focused on Accommodating or Avoiding Glycans.. Immunity. 43(6):1053-63.
Lee J H, Leaman DP, Kim AS, de la Peña ATorrents, Sliepen K, Yasmeen A, Derking R, Ramos A, de Taeye SW, Ozorowski G et al..  2015.  Antibodies to a conformational epitope on gp41 neutralize HIV-1 by destabilizing the Env spike.. Nat Commun. 6:8167.
He L, Cheng Y, Kong L, Azadnia P, Giang E, Kim J, Wood MR, Wilson IA, Law M, Zhu J.  2015.  Approaching rational epitope vaccine design for hepatitis C virus with meta-server and multivalent scaffolding.. Sci Rep. 5:12501.
Kong L, de la Peña ATorrents, Deller MC, Garces F, Sliepen K, Hua Y, Stanfield RL, Sanders RW, Wilson IA.  2015.  Complete epitopes for vaccine design derived from a crystal structure of the broadly neutralizing antibodies PGT128 and 8ANC195 in complex with an HIV-1 Env trimer.. Acta Crystallogr D Biol Crystallogr. 71(Pt 10):2099-108.
Derking R, Ozorowski G, Sliepen K, Yasmeen A, Cupo A, Torres JL, Julien J-P, Lee J H, van Montfort T, de Taeye SW et al..  2015.  Comprehensive Antigenic Map of a Cleaved Soluble HIV-1 Envelope Trimer.. PLoS Pathog. 11(3):e1004767.
Kong L, Wilson IA, Kwong PD.  2015.  Crystal structure of a fully glycosylated HIV-1 gp120 core reveals a stabilizing role for the glycan at Asn262.. Proteins. 83(3):590-6.

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