Found 36 results
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Allen JD, Sanders RW, Doores KJ, Crispin M.  2018.  Harnessing post-translational modifications for next-generation HIV immunogens.. Biochem Soc Trans. 46(3):691-698.
Behrens A-J, Kumar A, Medina-Ramírez M, Cupo A, Marshall K, Portillo VMCruz, Harvey DJ, Ozorowski G, Zitzmann N, Wilson IA et al..  2018.  Integrity of Glycosylation Processing of a Glycan-Depleted Trimeric HIV-1 Immunogen Targeting Key B-Cell Lineages.. J Proteome Res. 17(3):987-999.
Harvey DJ, Seabright GE, Vasiljevic S, Crispin M, Struwe WB.  2018.  Isomer Information from Ion Mobility Separation of High-Mannose Glycan Fragments.. J Am Soc Mass Spectrom. 29(5):972-988.
Watanabe Y, Vasiljevic S, Allen JD, Seabright GE, Duyvesteyn HME, Doores KJ, Crispin M, Struwe WB.  2018.  Signature of Antibody Domain Exchange by Native Mass Spectrometry and Collision-Induced Unfolding.. Anal Chem. 90(12):7325-7331.
Emsley P, Crispin M.  2018.  Structural analysis of glycoproteins: building N-linked glycans with Coot.. Acta Crystallogr D Struct Biol. 74(Pt 4):256-263.
Sarkar A, Bale S, Behrens A-J, Kumar S, Sharma SKumar, de Val N, Pallesen J, Irimia A, Diwanji DC, Stanfield RL et al..  2018.  Structure of a cleavage-independent HIV Env recapitulates the glycoprotein architecture of the native cleaved trimer.. Nat Commun. 9(1):1956.
Watanabe Y, Raghwani J, Allen JD, Seabright GE, Li S, Moser F, Huiskonen JT, Strecker T, Bowden TA, Crispin M.  2018.  Structure of the Lassa virus glycan shield provides a model for immunological resistance.. Proc Natl Acad Sci U S A. 115(28):7320-7325.
Yang L, Sharma SKumar, Cottrell C, Guenaga J, Tran K, Wilson R, Behrens A-J, Crispin M, de Val N, Wyatt RT.  2018.  Structure-Guided Redesign Improves NFL HIV Env Trimer Integrity and Identifies an Inter-Protomer Disulfide Permitting Post-Expression Cleavage.. Front Immunol. 9:1631.
Dey AK, Cupo A, Ozorowski G, Sharma VK, Behrens A-J, Go EP, Ketas TJ, Yasmeen A, Klasse PJ, Sayeed E et al..  2017.  cGMP production and analysis of BG505 SOSIP.664, an extensively glycosylated, trimeric HIV-1 envelope glycoprotein vaccine candidate.. Biotechnol Bioeng.
Medina-Ramírez M, Garces F, Escolano A, Skog P, de Taeye SW, Del Moral-Sanchez I, McGuire AT, Yasmeen A, Behrens A-J, Ozorowski G et al..  2017.  Design and crystal structure of a native-like HIV-1 envelope trimer that engages multiple broadly neutralizing antibody precursors in vivo.. J Exp Med. 214(9):2573-2590.
Voss JE, Andrabi R, McCoy LE, de Val N, Fuller RP, Messmer T, Su C-Y, Sok D, Khan SN, Garces F et al..  2017.  Elicitation of Neutralizing Antibodies Targeting the V2 Apex of the HIV Envelope Trimer in a Wild-Type Animal Model.. Cell Rep. 21(1):222-235.
Struwe WB, Stuckmann A, Behrens A-J, Pagel K, Crispin M.  2017.  Global N-Glycan Site Occupancy of HIV-1 gp120 by Metabolic Engineering and High-Resolution Intact Mass Spectrometry.. ACS Chem Biol. 12(2):357-361.
A de la Peña T, Julien J-P, de Taeye SW, Garces F, Guttman M, Ozorowski G, Pritchard LK, Behrens A-J, Go EP, Burger JA et al..  2017.  Improving the Immunogenicity of Native-like HIV-1 Envelope Trimers by Hyperstabilization.. Cell Rep. 20(8):1805-1817.
Behrens A-J, Harvey DJ, Milne E, Cupo A, Kumar A, Zitzmann N, Struwe WB, Moore JP, Crispin M.  2017.  Molecular Architecture of the Cleavage-Dependent Mannose Patch on a Soluble HIV-1 Envelope Glycoprotein Trimer.. J Virol. 91(2):pii:e01894-16.
Behrens A-J, Crispin M.  2017.  Structural principles controlling HIV envelope glycosylation.. Curr Opin Struct Biol. 44:125-133.
Hopper JTS, Ambrose S, Grant OC, Krumm SA, Allison TM, Degiacomi MT, Tully MD, Pritchard LK, Ozorowski G, Ward AB et al..  2017.  The Tetrameric Plant Lectin BanLec Neutralizes HIV through Bidentate Binding to Specific Viral Glycans.. Structure. 25(5):773-782.e5.
Behrens A-J, Vasiljevic S, Pritchard LK, Harvey DJ, Andev RS, Krumm SA, Struwe WB, Cupo A, Kumar A, Zitzmann N et al..  2016.  Composition and Antigenic Effects of Individual Glycan Sites of a Trimeric HIV-1 Envelope Glycoprotein.. Cell Rep.
van Gils MJ, van den Kerkhof TLGM, Ozorowski G, Cottrell CA, Sok D, Pauthner M, Pallesen J, de Val N, Yasmeen A, de Taeye SW et al..  2016.  An HIV-1 antibody from an elite neutralizer implicates the fusion peptide as a site of vulnerability.. Nat Microbiol. 2:16199.
Coss KP, Vasiljevic S, Pritchard LK, Krumm SA, Glaze M, Madzorera S, Moore PL, Crispin M, Doores KJ.  2016.  HIV-1 Glycan Density Drives the Persistence of the Mannose Patch within an Infected Individual.. J Virol. 90(24):11132-11144.
Krumm SA, Mohammed H, Le KM, Crispin M, Wrin T, Poignard P, Burton DR, Doores KJ.  2016.  Mechanisms of escape from the PGT128 family of anti-HIV broadly neutralizing antibodies.. Retrovirology. 13(1):8.
Crispin M, Zeltina A, Zitzmann N, Bowden TA.  2016.  Native functionality and therapeutic targeting of arenaviral glycoproteins.. Curr Opin Virol. 18:70-75.
Halldorsson S, Behrens A-J, Harlos K, Huiskonen JT, Elliott RM, Crispin M, Brennan B, Bowden TA.  2016.  Structure of a phleboviral envelope glycoprotein reveals a consolidated model of membrane fusion.. Proc Natl Acad Sci U S A. 113(26):7154-9.
Harvey DJ, Scarff CA, Edgeworth M, Struwe WB, Pagel K, Thalassinos K, Crispin M, Scrivens J.  2016.  Travelling-wave ion mobility and negative ion fragmentation of high-mannose N-glycans.. J Mass Spectrom. 51(3):219-35.
Harvey DJ, Scarff CA, Edgeworth M, Pagel K, Thalassinos K, Struwe WB, Crispin M, Scrivens JH.  2016.  Travelling-wave ion mobility mass spectrometry and negative ion fragmentation of hybrid and complex N-glycans.. J Mass Spectrom.
Stewart-Jones GBE, Soto C, Lemmin T, Chuang G-Y, Druz A, Kong R, Thomas PV, Wagh K, Zhou T, Behrens A-J et al..  2016.  Trimeric HIV-1-Env Structures Define Glycan Shields from Clades A, B, and G.. Cell. 165(4):813-26.