Publications

Found 24 results
Filters: Author is de Val, Natalia  [Clear All Filters]
2017
Morris CD, Azadnia P, de Val N, Vora N, Honda A, Giang E, Saye-Francisco K, Cheng Y, Lin X, Mann CJ et al..  2017.  Differential Antibody Responses to Conserved HIV-1 Neutralizing Epitopes in the Context of Multivalent Scaffolds and Native-Like gp140 Trimers.. MBio. 8(1):pii:e00036-17.
Voss JE, Andrabi R, McCoy LE, de Val N, Fuller RP, Messmer T, Su C-Y, Sok D, Khan SN, Garces F et al..  2017.  Elicitation of Neutralizing Antibodies Targeting the V2 Apex of the HIV Envelope Trimer in a Wild-Type Animal Model.. Cell Rep. 21(1):222-235.
Guenaga J, Garces F, de Val N, Stanfield RL, Dubrovskaya V, Higgins B, Carrette B, Ward AB, Wilson IA, Wyatt RT.  2017.  Glycine Substitution at Helix-to-Coil Transitions Facilitates the Structural Determination of a Stabilized Subtype C HIV Envelope Glycoprotein.. Immunity. 46(5):792-803.e3.
He L, Lin X, de Val N, Saye-Francisco KL, Mann CJ, Augst R, Morris CD, Azadnia P, Zhou B, Sok D et al..  2017.  Hidden Lineage Complexity of Glycan-Dependent HIV-1 Broadly Neutralizing Antibodies Uncovered by Digital Panning and Native-Like gp140 Trimer.. Front Immunol. 8:1025.
Landais E, Murrell B, Briney B, Murrell S, Rantalainen K, Berndsen ZT, Ramos A, Wickramasinghe L, Smith MLaird, Eren K et al..  2017.  HIV Envelope Glycoform Heterogeneity and Localized Diversity Govern the Initiation and Maturation of a V2 Apex Broadly Neutralizing Antibody Lineage.. Immunity. 47(5):990-1003.e9.
Ozorowski G, Pallesen J, de Val N, Lyumkis D, Cottrell CA, Torres JL, Copps J, Stanfield RL, Cupo A, Pugach P et al..  2017.  Open and closed structures reveal allostery and pliability in the HIV-1 envelope spike.. Nature. 547(7663):360-363.
Kulp DW, Steichen JM, Pauthner M, Hu X, Schiffner T, Liguori A, Cottrell CA, Havenar-Daughton C, Ozorowski G, Georgeson E et al..  2017.  Structure-based design of native-like HIV-1 envelope trimers to silence non-neutralizing epitopes and eliminate CD4 binding.. Nat Commun. 8(1):1655.
2015
Garces F, Lee J H, de Val N, de la Peña ATorrents, Kong L, Puchades C, Hua Y, Stanfield RL, Burton DR, Moore JP et al..  2015.  Affinity Maturation of a Potent Family of HIV Antibodies Is Primarily Focused on Accommodating or Avoiding Glycans.. Immunity. 43(6):1053-63.
Schiffner T, de Val N, Russell RA, de Taeye SW, de la Peña ATorrents, Ozorowski G, Kim HJ, Nieusma T, Brod F, Cupo A et al..  2015.  Chemical Cross-Linking Stabilizes Native-Like HIV-1 Envelope Glycoprotein Trimer Antigens.. J Virol. 90(2):813-28.
Sharma SKumar, de Val N, Bale S, Guenaga J, Tran K, Feng Y, Dubrovskaya V, Ward AB, Wyatt RT.  2015.  Cleavage-Independent HIV-1 Env Trimers Engineered as Soluble Native Spike Mimetics for Vaccine Design.. Cell Rep.
Lee J H, de Val N, Lyumkis D, Ward AB.  2015.  Model Building and Refinement of a Natively Glycosylated HIV-1 Env Protein by High-Resolution Cryoelectron Microscopy.. Structure. 23(10):1943-51.
Pugach P, Ozorowski G, Cupo A, Ringe R, Yasmeen A, de Val N, Derking R, Kim HJ, Korzun J, Golabek M et al..  2015.  A Native-Like SOSIP.664 Trimer Based on an HIV-1 Subtype B env Gene.. J Virol. 89(6):3380-95.
Guenaga J, Dubrovskaya V, de Val N, Sharma SK, Carrette B, Ward AB, Wyatt RT.  2015.  Structure-guided redesign increases the propensity of HIV Env to generate highly stable soluble trimers.. J Virol.
Guenaga J, de Val N, Tran K, Feng Y, Satchwell K, Ward AB, Wyatt RT.  2015.  Well-ordered trimeric HIV-1 subtype B and C soluble spike mimetics generated by negative selection display native-like properties.. PLoS Pathog. 11(1):e1004570.