Publications

Found 369 results
2016
Lee J H, Ozorowski G, Ward AB.  2016.  Cryo-EM structure of a native, fully glycosylated, cleaved HIV-1 envelope trimer.. Science. 351(6277):1043-8.
Irimia A, Sarkar A, Stanfield RL, Wilson IA.  2016.  Crystallographic Identification of Lipid as an Integral Component of the Epitope of HIV Broadly Neutralizing Antibody 4E10.. Immunity. 44(1):21-31.
Havenar-Daughton C, Lindqvist M, Heit A, Wu JE, Reiss SM, Kendric K, Bélanger S, Kasturi SPai, Landais E, Akondy RS et al..  2016.  CXCL13 is a plasma biomarker of germinal center activity.. Proc Natl Acad Sci U S A.
Dan JM, Arlehamn CSLindesta, Weiskopf D, Antunes Rda Silva, Havenar-Daughton C, Reiss SM, Brigger M, Bothwell M, Sette A, Crotty S.  2016.  A Cytokine-Independent Approach To Identify Antigen-Specific Human Germinal Center T Follicular Helper Cells and Rare Antigen-Specific CD4+ T Cells in Blood.. J Immunol.
Havenar-Daughton C, Reiss SM, Carnathan DG, Wu JE, Kendric K, de la Peña ATorrents, Kasturi SPai, Dan JM, Bothwell M, Sanders RW et al..  2016.  Cytokine-Independent Detection of Antigen-Specific Germinal Center T Follicular Helper Cells in Immunized Nonhuman Primates Using a Live Cell Activation-Induced Marker Technique.. J Immunol.
Ellebedy AH, Jackson KJL, Kissick HT, Nakaya HI, Davis CW, Roskin KM, McElroy AK, Oshansky CM, Elbein R, Thomas S et al..  2016.  Defining antigen-specific plasmablast and memory B cell subsets in human blood after viral infection or vaccination.. Nat Immunol. 17(10):1226-34.
Havenar-Daughton C, Carnathan DG, de la Peña ATorrents, Pauthner M, Briney B, Reiss SM, Wood JS, Kaushik K, van Gils MJ, Rosales SL et al..  2016.  Direct Probing of Germinal Center Responses Reveals Immunological Features and Bottlenecks for Neutralizing Antibody Responses to HIV Env Trimer.. Cell Rep. 17(9):2195-2209.
MacLeod DT, Choi NM, Briney B, Garces F, Ver LS, Landais E, Murrell B, Wrin T, Kilembe W, Liang C-H et al..  2016.  Early Antibody Lineage Diversification and Independent Limb Maturation Lead to Broad HIV-1 Neutralization Targeting the Env High-Mannose Patch.. Immunity. 44(5):1215-26.
Lu C-L, Murakowski DK, Bournazos S, Schoofs T, Sarkar D, Halper-Stromberg A, Horwitz JA, Nogueira L, Golijanin J, Gazumyan A et al..  2016.  Enhanced clearance of HIV-1-infected cells by broadly neutralizing antibodies against HIV-1 in vivo.. Science. 352(6288):1001-4.
Kong R, Xu K, Zhou T, Acharya P, Lemmin T, Liu K, Ozorowski G, Soto C, Taft JD, Bailer RT et al..  2016.  Fusion peptide of HIV-1 as a site of vulnerability to neutralizing antibody.. Science. 352(6287):828-33.
Ingale J, Stano A, Guenaga J, Sharma SKumar, Nemazee D, Zwick MB, Wyatt RT.  2016.  High-Density Array of Well-Ordered HIV-1 Spikes on Synthetic Liposomal Nanoparticles Efficiently Activate B Cells.. Cell Rep. 15(9):1986-99.
Wang Y, Sundling C, Wilson R, O'Dell S, Chen Y, Dai K, Phad GE, Zhu J, Xiao Y, Mascola JR et al..  2016.  High-Resolution Longitudinal Study of HIV-1 Env Vaccine-Elicited B Cell Responses to the Virus Primary Receptor Binding Site Reveals Affinity Maturation and Clonal Persistence.. J Immunol.
Sok D, Burton DR.  2016.  HIV Broadly Neutralizing Antibodies: Taking Good Care Of The 98.. Immunity. 45(5):958-960.
Steichen JM, Kulp DW, Tokatlian T, Escolano A, Dosenovic P, Stanfield RL, McCoy LE, Ozorowski G, Hu X, Kalyuzhniy O et al..  2016.  HIV Vaccine Design to Target Germline Precursors of Glycan-Dependent Broadly Neutralizing Antibodies.. Immunity.
Scheid JF, Horwitz JA, Bar-On Y, Kreider EF, Lu C-L, Lorenzi JCC, Feldmann A, Braunschweig M, Nogueira L, Oliveira T et al..  2016.  HIV-1 antibody 3BNC117 suppresses viral rebound in humans during treatment interruption.. Nature.
van Gils MJ, van den Kerkhof TLGM, Ozorowski G, Cottrell CA, Sok D, Pauthner M, Pallesen J, de Val N, Yasmeen A, de Taeye SW et al..  2016.  An HIV-1 antibody from an elite neutralizer implicates the fusion peptide as a site of vulnerability.. Nat Microbiol. 2:16199.
Jardine JG, Kulp DW, Havenar-Daughton C, Sarkar A, Briney B, Sok D, Sesterhenn F, Ereño-Orbea J, Kalyuzhniy O, Deresa I et al..  2016.  HIV-1 broadly neutralizing antibody precursor B cells revealed by germline-targeting immunogen.. Science. 351(6280):1458-63.
Chen Y, Wilson R, O'Dell S, Guenaga J, Feng Y, Tran K, Chiang C-I, Arendt HE, DeStefano J, Mascola JR et al..  2016.  An HIV-1 Env-Antibody Complex Focuses Antibody Responses to Conserved Neutralizing Epitopes.. J Immunol. 197(10):3982-3998.
van den Kerkhof TLGM, de Taeye SW, Boeser-Nunnink BD, Burton DR, Kootstra NA, Schuitemaker H, Sanders RW, van Gils MJ.  2016.  HIV-1 escapes from N332-directed antibody neutralization in an elite neutralizer by envelope glycoprotein elongation and introduction of unusual disulfide bonds.. Retrovirology. 13(1):48.
Schoofs T, Klein F, Braunschweig M, Kreider EF, Feldmann A, Nogueira L, Oliveira T, Lorenzi JCC, Parrish EH, Learn GH et al..  2016.  HIV-1 therapy with monoclonal antibody 3BNC117 elicits host immune responses against HIV-1.. Science. 352(6288):997-1001.
Dai K, Khan SN, Wang Y, He L, Guenaga J, Ingale J, Sundling C, O'Dell S, McKee K, Phad G et al..  2016.  HIV-1 Vaccine-elicited Antibodies Reverted to Their Inferred Naive Germline Reveal Associations between Binding Affinity and in vivo Activation.. Sci Rep. 6:20987.
McCoy LE, van Gils MJ, Ozorowski G, Messmer T, Briney B, Voss JE, Kulp DW, Macauley MS, Sok D, Pauthner M et al..  2016.  Holes in the Glycan Shield of the Native HIV Envelope Are a Target of Trimer-Elicited Neutralizing Antibodies.. Cell Rep. 16(9):2327-38.
Gitlin AD, von Boehmer L, Gazumyan A, Shulman, iv Z, Oliveira TY, Nussenzweig MC.  2016.  Independent Roles of Switching and Hypermutation in the Development and Persistence of B Lymphocyte Memory.. Immunity.
Tian M, Cheng C, Chen X, Duan H, Cheng H-L, Dao M, Sheng Z, Kimble M, Wang L, Lin S et al..  2016.  Induction of HIV Neutralizing Antibody Lineages in Mice with Diverse Precursor Repertoires.. Cell. 166(6):1471-1484.e18.
Bornholdt ZA, Turner HL, Murin CD, Li W, Sok D, Souders CA, Piper AE, Goff A, Shamblin JD, Wollen SE et al..  2016.  Isolation of potent neutralizing antibodies from a survivor of the 2014 Ebola virus outbreak.. Science. 351(6277):1078-83.

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