Publications

Kong L, He L, de Val N, Vora N, Morris CD, Azadnia P, Sok D, Zhou B, Burton DR, Ward AB et al..  2016.  Uncleaved prefusion-optimized gp140 trimers derived from analysis of HIV-1 envelope metastability.. Nat Commun. 7:12040.

Gardner MR, Kattenhorn LM, Kondur HR, von Schaewen M, Dorfman T, Chiang JJ, Haworth KG, Decker JM, Alpert MD, Bailey CC et al..  2015.  AAV-expressed eCD4-Ig provides durable protection from multiple SHIV challenges.. Nature. 519(7541):87-91.

Garces F, Lee J H, de Val N, de la Peña ATorrents, Kong L, Puchades C, Hua Y, Stanfield RL, Burton DR, Moore JP et al..  2015.  Affinity Maturation of a Potent Family of HIV Antibodies Is Primarily Focused on Accommodating or Avoiding Glycans.. Immunity. 43(6):1053-63.

Lee J H, Leaman DP, Kim AS, de la Peña ATorrents, Sliepen K, Yasmeen A, Derking R, Ramos A, de Taeye SW, Ozorowski G et al..  2015.  Antibodies to a conformational epitope on gp41 neutralize HIV-1 by destabilizing the Env spike.. Nat Commun. 6:8167.

Burton DR, Mascola JR.  2015.  Antibody responses to envelope glycoproteins in HIV-1 infection.. Nat Immunol. 16(6):571-6.

Derking R, Ozorowski G, Sliepen K, Yasmeen A, Cupo A, Torres JL, Julien J-P, Lee J H, van Montfort T, de Taeye SW et al..  2015.  Comprehensive Antigenic Map of a Cleaved Soluble HIV-1 Envelope Trimer.. PLoS Pathog. 11(3):e1004767.

Sanders RW, van Gils MJ, Derking R, Sok D, Ketas TJ, Burger JA, Ozorowski G, Cupo A, Simonich C, Goo L et al..  2015.  HIV-1 neutralizing antibodies induced by native-like envelope trimers.. Science.

Jardine JG, Ota T, Sok D, Pauthner M, Kulp DW, Kalyuzhniy O, Skog PD, Thinnes TC, Bhullar D, Briney B et al..  2015.  HIV-1 VACCINES. Priming a broadly neutralizing antibody response to HIV-1 using a germline-targeting immunogen.. Science. 349(6244):156-61.

Andrabi R, Voss JE, Liang C-H, Briney B, McCoy LE, Wu C-Y, Wong C-H, Poignard P, Burton DR.  2015.  Identification of Common Features in Prototype Broadly Neutralizing Antibodies to HIV Envelope V2 Apex to Facilitate Vaccine Design.. Immunity. 43(5):959-73.

McCoy LE, Falkowska E, Doores KJ, Le K, Sok D, van Gils MJ, Euler Z, Burger JA, Seaman MS, Sanders RW et al..  2015.  Incomplete Neutralization and Deviation from Sigmoidal Neutralization Curves for HIV Broadly Neutralizing Monoclonal Antibodies.. PLoS Pathog. 11(8):e1005110.

Wang S, Mata-Fink J, Kriegsman B, Hanson M, Irvine DJ, Eisen HN, Burton DR, K Wittrup D, Kardar M, Chakraborty AK.  2015.  Manipulating the Selection Forces during Affinity Maturation to Generate Cross-Reactive HIV Antibodies.. Cell. 160(4):785-97.

Hu JK, Crampton JC, Cupo A, Ketas T, van Gils MJ, Sliepen K, de Taeye SW, Sok D, Ozorowski G, Deresa I et al..  2015.  Murine Antibody Responses to Cleaved Soluble HIV-1 Envelope Trimers Are Highly Restricted in Specificity.. J Virol. 89(20):10383-98.

Pugach P, Ozorowski G, Cupo A, Ringe R, Yasmeen A, de Val N, Derking R, Kim HJ, Korzun J, Golabek M et al..  2015.  A Native-Like SOSIP.664 Trimer Based on an HIV-1 Subtype B env Gene.. J Virol. 89(6):3380-95.

Pritchard LK, Vasiljevic S, Ozorowski G, Seabright GE, Cupo A, Ringe R, Kim HJ, Sanders RW, Doores KJ, Burton DR et al..  2015.  Structural Constraints Determine the Glycosylation of HIV-1 Envelope Trimers.. Cell Rep.

Zhou T, Lynch RM, Chen L, Acharya P, Wu X, Doria-Rose NA, M Joyce G, Lingwood D, Soto C, Bailer RT et al..  2015.  Structural Repertoire of HIV-1-Neutralizing Antibodies Targeting the CD4 Supersite in 14 Donors.. Cell. 161(6):1280-92.

Doores KJ, Kong L, Krumm SA, Le KM, Sok D, Laserson U, Garces F, Poignard P, Wilson IA, Burton DR.  2015.  Two classes of broadly neutralizing antibodies within a single lineage directed to the high-mannose patch of HIV envelope.. J Virol. 89(2):1105-18.

Eroshkin AM, Leblanc A, Weekes D, Post K, Li Z, Rajput A, Butera ST, Burton DR, Godzik A.  2014.  bNAber: database of broadly neutralizing HIV antibodies.. Nucleic Acids Res. 42(Database issue):D1133-9.

Falkowska E, Le KM, Ramos A, Doores KJ, Lee J H, Blattner C, Ramirez A, Derking R, van Gils MJ, Liang C-H et al..  2014.  Broadly Neutralizing HIV Antibodies Define a Glycan-Dependent Epitope on the Prefusion Conformation of gp41 on Cleaved Envelope Trimers.. Immunity. 40(5):657-68.

Li Q, Zeng M, Duan L, Voss JE, Smith AJ, Pambuccian S, Shang L, Wietgrefe S, Southern PJ, Reilly CS et al..  2014.  Live simian immunodeficiency virus vaccine correlate of protection: local antibody production and concentration on the path of virus entry.. J Immunol. 193(6):3113-25.

Shingai M, Donau OK, Plishka RJ, Buckler-White A, Mascola JR, Nabel GJ, Nason MC, Montefiori D, Moldt B, Poignard P et al..  2014.  Passive transfer of modest titers of potent and broadly neutralizing anti-HIV monoclonal antibodies block SHIV infection in macaques.. J Exp Med. 211(10):2061-74.

Trist HM, Tan PSzee, Wines BD, Ramsland PA, Orlowski E, Stubbs J, Gardiner EE, Pietersz GA, Kent SJ, Stratov I et al..  2014.  Polymorphisms and interspecies differences of the activating and inhibitory FcγRII of Macaca nemestrina influence the binding of human IgG subclasses.. J Immunol. 192(2):792-803.

Sok D, Doores KJ, Briney B, Le KM, Saye-Francisco KL, Ramos A, Kulp DW, Julien J-P, Menis S, Wickramasinghe L et al..  2014.  Promiscuous Glycan Site Recognition by Antibodies to the High-Mannose Patch of gp120 Broadens Neutralization of HIV.. Sci Transl Med. 6(236):236ra63.

Sok D, van Gils MJ, Pauthner M, Julien J-P, Saye-Francisco KL, Hsueh J, Briney B, Lee J H, Le KM, Lee PS et al..  2014.  Recombinant HIV envelope trimer selects for quaternary-dependent antibodies targeting the trimer apex.. Proc Natl Acad Sci U S A. 111(49):17624-9.

Del Prete GQ, Ailers B, Moldt B, Keele BF, Estes JD, Rodriguez A, Sampias M, Oswald K, Fast R, Trubey CM et al..  2014.  Selection of unadapted, pathogenic SHIVs encoding newly transmitted HIV-1 envelope proteins.. Cell Host Microbe. 16(3):412-8.

Blattner C, Lee J H, Sliepen K, Derking R, Falkowska E, de la Peña ATorrents, Cupo A, Julien J-P, van Gils M, Lee PS et al..  2014.  Structural Delineation of a Quaternary, Cleavage-Dependent Epitope at the gp41-gp120 Interface on Intact HIV-1 Env Trimers.. Immunity. 40(5):669-80.