Publications

Found 369 results
2015
Sharma SKumar, de Val N, Bale S, Guenaga J, Tran K, Feng Y, Dubrovskaya V, Ward AB, Wyatt RT.  2015.  Cleavage-Independent HIV-1 Env Trimers Engineered as Soluble Native Spike Mimetics for Vaccine Design.. Cell Rep.
Kong L, de la Peña ATorrents, Deller MC, Garces F, Sliepen K, Hua Y, Stanfield RL, Sanders RW, Wilson IA.  2015.  Complete epitopes for vaccine design derived from a crystal structure of the broadly neutralizing antibodies PGT128 and 8ANC195 in complex with an HIV-1 Env trimer.. Acta Crystallogr D Biol Crystallogr. 71(Pt 10):2099-108.
Derking R, Ozorowski G, Sliepen K, Yasmeen A, Cupo A, Torres JL, Julien J-P, Lee J H, van Montfort T, de Taeye SW et al..  2015.  Comprehensive Antigenic Map of a Cleaved Soluble HIV-1 Envelope Trimer.. PLoS Pathog. 11(3):e1004767.
Edlefsen PT, Rolland M, Hertz T, Tovanabutra S, Gartland AJ, DeCamp AC, Magaret CA, Ahmed H, Gottardo R, Juraska M et al..  2015.  Comprehensive sieve analysis of breakthrough HIV-1 sequences in the RV144 vaccine efficacy trial.. PLoS Comput Biol. 11(2):e1003973.
He L, Zhu J.  2015.  Computational tools for epitope vaccine design and evaluation.. Curr Opin Virol. 11:103-112.
Ingale J, Wyatt RT.  2015.  Coupling of HIV-1 gp120-derived Core Protein to Paramagnetic Beads and Adsorption Assays.. Bio Protoc. 5(20)
Kong L, Wilson IA, Kwong PD.  2015.  Crystal structure of a fully glycosylated HIV-1 gp120 core reveals a stabilizing role for the glycan at Asn262.. Proteins. 83(3):590-6.
Stanfield RL, De Castro C, Marzaioli AM, Wilson IA, Pantophlet R.  2015.  Crystal structure of the HIV neutralizing antibody 2G12 in complex with a bacterial oligosaccharide analog of mammalian oligomannose.. Glycobiology. 25(4):412-9.
Julien J-P, Lee J H, Ozorowski G, Hua Y, de la Peña ATorrents, de Taeye SW, Nieusma T, Cupo A, Yasmeen A, Golabek M et al..  2015.  Design and structure of two HIV-1 clade C SOSIP.664 trimers that increase the arsenal of native-like Env immunogens.. Proc Natl Acad Sci U S A.
Bitto D, Harvey DJ, Halldorsson S, Doores KJ, Pritchard LK, Huiskonen JT, Bowden TA, Crispin M.  2015.  Determination of N-linked Glycosylation in Viral Glycoproteins by Negative Ion Mass Spectrometry and Ion Mobility.. Methods Mol Biol. 1331:93-121.
Murugan R, Imkeller K, Busse CE, Wardemann H.  2015.  Direct high-throughput amplification and sequencing of immunoglobulin genes from single human B cells.. Eur J Immunol. 45(9):2698-700.
Sliepen K, van Montfort T, Ozorowski G, Pritchard LK, Crispin M, Ward AB, Sanders RW.  2015.  Engineering and Characterization of a Fluorescent Native-Like HIV-1 Envelope Glycoprotein Trimer.. Biomolecules. 5(4):2919-34.
Heesters BA, Lindqvist M, Vagefi PA, Scully EP, Schildberg FA, Altfeld M, Walker BD, Kaufmann DE, Carroll MC.  2015.  Follicular Dendritic Cells Retain Infectious HIV in Cycling Endosomes.. PLoS Pathog. 11(12):e1005285.
Pritchard LK, Spencer DIR, Royle L, Bonomelli C, Seabright GE, Behrens A-J, Kulp DW, Menis S, Krumm SA, Dunlop CD et al..  2015.  Glycan clustering stabilizes the mannose patch of HIV-1 and preserves vulnerability to broadly neutralizing antibodies.. Nat Commun. 6:7479.
Pritchard LK, Spencer DIR, Royle L, Vasiljevic S, Krumm SA, Doores KJ, Crispin M.  2015.  Glycan Microheterogeneity at the PGT135 Antibody Recognition Site on HIV-1 gp120 Reveals a Molecular Mechanism for Neutralization Resistance.. J Virol. 89(13):6952-9.
Gounder K, Padayachi N, Mann JK, Radebe M, Mokgoro M, van der Stok M, Mkhize L, Mncube Z, Jaggernath M, Reddy T et al..  2015.  High Frequency of Transmitted HIV-1 Gag HLA Class I-Driven Immune Escape Variants but Minimal Immune Selection over the First Year of Clade C Infection.. PLoS One. 10(3):e0119886.
Ranasinghe S, Soghoian DZ, Lindqvist M, Ghebremichael M, Donaghey F, Carrington M, Seaman MS, Kaufmann DE, Walker BD, Porichis F.  2015.  HIV-1 antibody neutralization breadth is associated with enhanced HIV-specific CD4+ T cell responses.. J Virol.
Cohn LB, Silva IT, Oliveira TY, Rosales RA, Parrish EH, Learn GH, Hahn BH, Czartoski JL, McElrath JM, Lehmann C et al..  2015.  HIV-1 Integration Landscape during Latent and Active Infection.. Cell. 160(3):420-32.
Sanders RW, van Gils MJ, Derking R, Sok D, Ketas TJ, Burger JA, Ozorowski G, Cupo A, Simonich C, Goo L et al..  2015.  HIV-1 neutralizing antibodies induced by native-like envelope trimers.. Science.
Jardine JG, Ota T, Sok D, Pauthner M, Kulp DW, Kalyuzhniy O, Skog PD, Thinnes TC, Bhullar D, Briney B et al..  2015.  HIV-1 VACCINES. Priming a broadly neutralizing antibody response to HIV-1 using a germline-targeting immunogen.. Science. 349(6244):156-61.
Andrabi R, Voss JE, Liang C-H, Briney B, McCoy LE, Wu C-Y, Wong C-H, Poignard P, Burton DR.  2015.  Identification of Common Features in Prototype Broadly Neutralizing Antibodies to HIV Envelope V2 Apex to Facilitate Vaccine Design.. Immunity. 43(5):959-73.
Wang TT, Ravetch JV.  2015.  Immune complexes: not just an innocent bystander in chronic viral infection.. Immunity. 42(2):213-5.
Dosenovic P, von Boehmer L, Escolano A, Jardine J, Freund NT, Gitlin AD, McGuire AT, Kulp DW, Oliveira T, Scharf L et al..  2015.  Immunization for HIV-1 Broadly Neutralizing Antibodies in Human Ig Knockin Mice.. Cell. 161(7):1505-15.
Leaman DP, Lee J H, Ward AB, Zwick MB.  2015.  Immunogenic Display of Purified Chemically Cross-Linked HIV-1 Spikes.. J Virol. 89(13):6725-45.
de Taeye SW, Ozorowski G, de la Peña ATorrents, Guttman M, Julien J-P, van den Kerkhof TLGM, Burger JA, Pritchard LK, Pugach P, Yasmeen A et al..  2015.  Immunogenicity of Stabilized HIV-1 Envelope Trimers with Reduced Exposure of Non-neutralizing Epitopes.. Cell. 163(7):1702-15.

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