Publications

Found 385 results
2015
Bitto D, Harvey DJ, Halldorsson S, Doores KJ, Pritchard LK, Huiskonen JT, Bowden TA, Crispin M.  2015.  Determination of N-linked Glycosylation in Viral Glycoproteins by Negative Ion Mass Spectrometry and Ion Mobility.. Methods Mol Biol. 1331:93-121.
Murugan R, Imkeller K, Busse CE, Wardemann H.  2015.  Direct high-throughput amplification and sequencing of immunoglobulin genes from single human B cells.. Eur J Immunol. 45(9):2698-700.
Sliepen K, van Montfort T, Ozorowski G, Pritchard LK, Crispin M, Ward AB, Sanders RW.  2015.  Engineering and Characterization of a Fluorescent Native-Like HIV-1 Envelope Glycoprotein Trimer.. Biomolecules. 5(4):2919-34.
Heesters BA, Lindqvist M, Vagefi PA, Scully EP, Schildberg FA, Altfeld M, Walker BD, Kaufmann DE, Carroll MC.  2015.  Follicular Dendritic Cells Retain Infectious HIV in Cycling Endosomes.. PLoS Pathog. 11(12):e1005285.
Pritchard LK, Spencer DIR, Royle L, Bonomelli C, Seabright GE, Behrens A-J, Kulp DW, Menis S, Krumm SA, Dunlop CD et al..  2015.  Glycan clustering stabilizes the mannose patch of HIV-1 and preserves vulnerability to broadly neutralizing antibodies.. Nat Commun. 6:7479.
Pritchard LK, Spencer DIR, Royle L, Vasiljevic S, Krumm SA, Doores KJ, Crispin M.  2015.  Glycan Microheterogeneity at the PGT135 Antibody Recognition Site on HIV-1 gp120 Reveals a Molecular Mechanism for Neutralization Resistance.. J Virol. 89(13):6952-9.
Gounder K, Padayachi N, Mann JK, Radebe M, Mokgoro M, van der Stok M, Mkhize L, Mncube Z, Jaggernath M, Reddy T et al..  2015.  High Frequency of Transmitted HIV-1 Gag HLA Class I-Driven Immune Escape Variants but Minimal Immune Selection over the First Year of Clade C Infection.. PLoS One. 10(3):e0119886.
Ranasinghe S, Soghoian DZ, Lindqvist M, Ghebremichael M, Donaghey F, Carrington M, Seaman MS, Kaufmann DE, Walker BD, Porichis F.  2015.  HIV-1 antibody neutralization breadth is associated with enhanced HIV-specific CD4+ T cell responses.. J Virol.
Cohn LB, Silva IT, Oliveira TY, Rosales RA, Parrish EH, Learn GH, Hahn BH, Czartoski JL, McElrath JM, Lehmann C et al..  2015.  HIV-1 Integration Landscape during Latent and Active Infection.. Cell. 160(3):420-32.
Sanders RW, van Gils MJ, Derking R, Sok D, Ketas TJ, Burger JA, Ozorowski G, Cupo A, Simonich C, Goo L et al..  2015.  HIV-1 neutralizing antibodies induced by native-like envelope trimers.. Science.
Jardine JG, Ota T, Sok D, Pauthner M, Kulp DW, Kalyuzhniy O, Skog PD, Thinnes TC, Bhullar D, Briney B et al..  2015.  HIV-1 VACCINES. Priming a broadly neutralizing antibody response to HIV-1 using a germline-targeting immunogen.. Science. 349(6244):156-61.
Andrabi R, Voss JE, Liang C-H, Briney B, McCoy LE, Wu C-Y, Wong C-H, Poignard P, Burton DR.  2015.  Identification of Common Features in Prototype Broadly Neutralizing Antibodies to HIV Envelope V2 Apex to Facilitate Vaccine Design.. Immunity. 43(5):959-73.
Wang TT, Ravetch JV.  2015.  Immune complexes: not just an innocent bystander in chronic viral infection.. Immunity. 42(2):213-5.
Dosenovic P, von Boehmer L, Escolano A, Jardine J, Freund NT, Gitlin AD, McGuire AT, Kulp DW, Oliveira T, Scharf L et al..  2015.  Immunization for HIV-1 Broadly Neutralizing Antibodies in Human Ig Knockin Mice.. Cell. 161(7):1505-15.
Leaman DP, Lee J H, Ward AB, Zwick MB.  2015.  Immunogenic Display of Purified Chemically Cross-Linked HIV-1 Spikes.. J Virol. 89(13):6725-45.
de Taeye SW, Ozorowski G, de la Peña ATorrents, Guttman M, Julien J-P, van den Kerkhof TLGM, Burger JA, Pritchard LK, Pugach P, Yasmeen A et al..  2015.  Immunogenicity of Stabilized HIV-1 Envelope Trimers with Reduced Exposure of Non-neutralizing Epitopes.. Cell. 163(7):1702-15.
McCoy LE, Falkowska E, Doores KJ, Le K, Sok D, van Gils MJ, Euler Z, Burger JA, Seaman MS, Sanders RW et al..  2015.  Incomplete Neutralization and Deviation from Sigmoidal Neutralization Curves for HIV Broadly Neutralizing Monoclonal Antibodies.. PLoS Pathog. 11(8):e1005110.
Ringe RP, Yasmeen A, Ozorowski G, Go EP, Pritchard LK, Guttman M, Ketas TA, Cottrell CA, Wilson IA, Sanders RW et al..  2015.  Influences on the design and purification of soluble, recombinant native-like HIV-1 envelope glycoprotein trimers.. J Virol.
Ward AB, Wilson IA.  2015.  Insights into the trimeric HIV-1 envelope glycoprotein structure.. Trends Biochem Sci.
Galimidi RP, Klein JS, Politzer MS, Bai S, Seaman MS, Nussenzweig MC, West AP, Bjorkman PJ.  2015.  Intra-Spike Crosslinking Overcomes Antibody Evasion by HIV-1.. Cell. 160(3):433-46.
Harvey DJ, Crispin M, Bonomelli C, Scrivens JH.  2015.  Ion Mobility Mass Spectrometry for Ion Recovery and Clean-Up of MS and MS/MS Spectra Obtained from Low Abundance Viral Samples.. J Am Soc Mass Spectrom. 26(10):1754-67.
Ingale J, Wyatt RT.  2015.  Kinetic Analysis of Monoclonal Antibody Binding to HIV-1 gp120-derived Hyperglycosylated Cores.. Bio Protoc. 5(20)
Wang S, Mata-Fink J, Kriegsman B, Hanson M, Irvine DJ, Eisen HN, Burton DR, K Wittrup D, Kardar M, Chakraborty AK.  2015.  Manipulating the Selection Forces during Affinity Maturation to Generate Cross-Reactive HIV Antibodies.. Cell. 160(4):785-97.
Lee J H, de Val N, Lyumkis D, Ward AB.  2015.  Model Building and Refinement of a Natively Glycosylated HIV-1 Env Protein by High-Resolution Cryoelectron Microscopy.. Structure. 23(10):1943-51.
Hu JK, Crampton JC, Cupo A, Ketas T, van Gils MJ, Sliepen K, de Taeye SW, Sok D, Ozorowski G, Deresa I et al..  2015.  Murine Antibody Responses to Cleaved Soluble HIV-1 Envelope Trimers Are Highly Restricted in Specificity.. J Virol. 89(20):10383-98.

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