Publications

Found 397 results
2015
Dosenovic P, von Boehmer L, Escolano A, Jardine J, Freund NT, Gitlin AD, McGuire AT, Kulp DW, Oliveira T, Scharf L et al..  2015.  Immunization for HIV-1 Broadly Neutralizing Antibodies in Human Ig Knockin Mice.. Cell. 161(7):1505-15.
Leaman DP, Lee J H, Ward AB, Zwick MB.  2015.  Immunogenic Display of Purified Chemically Cross-Linked HIV-1 Spikes.. J Virol. 89(13):6725-45.
de Taeye SW, Ozorowski G, de la Peña ATorrents, Guttman M, Julien J-P, van den Kerkhof TLGM, Burger JA, Pritchard LK, Pugach P, Yasmeen A et al..  2015.  Immunogenicity of Stabilized HIV-1 Envelope Trimers with Reduced Exposure of Non-neutralizing Epitopes.. Cell. 163(7):1702-15.
McCoy LE, Falkowska E, Doores KJ, Le K, Sok D, van Gils MJ, Euler Z, Burger JA, Seaman MS, Sanders RW et al..  2015.  Incomplete Neutralization and Deviation from Sigmoidal Neutralization Curves for HIV Broadly Neutralizing Monoclonal Antibodies.. PLoS Pathog. 11(8):e1005110.
Ringe RP, Yasmeen A, Ozorowski G, Go EP, Pritchard LK, Guttman M, Ketas TA, Cottrell CA, Wilson IA, Sanders RW et al..  2015.  Influences on the design and purification of soluble, recombinant native-like HIV-1 envelope glycoprotein trimers.. J Virol.
Ward AB, Wilson IA.  2015.  Insights into the trimeric HIV-1 envelope glycoprotein structure.. Trends Biochem Sci.
Galimidi RP, Klein JS, Politzer MS, Bai S, Seaman MS, Nussenzweig MC, West AP, Bjorkman PJ.  2015.  Intra-Spike Crosslinking Overcomes Antibody Evasion by HIV-1.. Cell. 160(3):433-46.
Harvey DJ, Crispin M, Bonomelli C, Scrivens JH.  2015.  Ion Mobility Mass Spectrometry for Ion Recovery and Clean-Up of MS and MS/MS Spectra Obtained from Low Abundance Viral Samples.. J Am Soc Mass Spectrom. 26(10):1754-67.
Ingale J, Wyatt RT.  2015.  Kinetic Analysis of Monoclonal Antibody Binding to HIV-1 gp120-derived Hyperglycosylated Cores.. Bio Protoc. 5(20)
Wang S, Mata-Fink J, Kriegsman B, Hanson M, Irvine DJ, Eisen HN, Burton DR, K Wittrup D, Kardar M, Chakraborty AK.  2015.  Manipulating the Selection Forces during Affinity Maturation to Generate Cross-Reactive HIV Antibodies.. Cell. 160(4):785-97.
Lee J H, de Val N, Lyumkis D, Ward AB.  2015.  Model Building and Refinement of a Natively Glycosylated HIV-1 Env Protein by High-Resolution Cryoelectron Microscopy.. Structure. 23(10):1943-51.
Hu JK, Crampton JC, Cupo A, Ketas T, van Gils MJ, Sliepen K, de Taeye SW, Sok D, Ozorowski G, Deresa I et al..  2015.  Murine Antibody Responses to Cleaved Soluble HIV-1 Envelope Trimers Are Highly Restricted in Specificity.. J Virol. 89(20):10383-98.
Pugach P, Ozorowski G, Cupo A, Ringe R, Yasmeen A, de Val N, Derking R, Kim HJ, Korzun J, Golabek M et al..  2015.  A Native-Like SOSIP.664 Trimer Based on an HIV-1 Subtype B env Gene.. J Virol. 89(6):3380-95.
Alsahafi N, Ding S, Richard J, Markle T, Brassard N, Walker B, Lewis GK, Kaufmann DE, Brockman MA, Finzi A.  2015.  Nef Proteins from HIV-1 Elite Controllers Are Inefficient at Preventing Antibody-Dependent Cellular Cytotoxicity.. J Virol. 90(6):2993-3002.
Freund NT, Horwitz JA, Nogueira L, Sievers SA, Scharf L, Scheid JF, Gazumyan A, Liu C, Velinzon K, Goldenthal A et al..  2015.  A New Glycan-Dependent CD4-Binding Site Neutralizing Antibody Exerts Pressure on HIV-1 In Vivo.. PLoS Pathog. 11(10):e1005238.
Martin-Gayo E, Buzon MJose, Ouyang Z, Hickman T, Cronin J, Pimenova D, Walker BD, Lichterfeld M, Yu XG.  2015.  Potent Cell-Intrinsic Immune Responses in Dendritic Cells Facilitate HIV-1-Specific T Cell Immunity in HIV-1 Elite Controllers.. PLoS Pathog. 11(6):e1004930.
Sliepen K, Ozorowski G, Burger JA, van Montfort T, Stunnenberg M, LaBranche C, Montefiori DC, Moore JP, Ward AB, Sanders RW.  2015.  Presenting native-like HIV-1 envelope trimers on ferritin nanoparticles improves their immunogenicity.. Retrovirology. 12:82.
Martinez P, Sundling C, O'Dell S, Mascola JR, Wyatt RT, Karlsson Hedestam GB.  2015.  Primate immune responses to HIV-1 Env formulated in the saponin-based adjuvant AbISCO-100 in the presence or absence of TLR9 co-stimulation.. Sci Rep. 5:8925.
Willis JR, Sapparapu G, Murrell S, Julien J-P, Singh V, King HG, Xia Y, Pickens JA, Labranche CC, Slaughter JC et al..  2015.  Redesigned HIV antibodies exhibit enhanced neutralizing potency and breadth.. J Clin Invest. 125(6):2523-31.
Cubas R, van Grevenynghe J, Wills S, Kardava L, Santich BH, Buckner CM, Muir R, Tardif V, Nichols C, Procopio F et al..  2015.  Reversible Reprogramming of Circulating Memory T Follicular Helper Cell Function during Chronic HIV Infection.. J Immunol. 195(12):5625-36.
Dai K, He L, Khan SN, O'Dell S, McKee K, Tran K, Li Y, Sundling C, Morris CD, Mascola JR et al..  2015.  Rhesus Macaque B-Cell Responses to an HIV-1 Trimer Vaccine Revealed by Unbiased Longitudinal Repertoire Analysis.. MBio. 6(6):e01375-15.
Richard J, Veillette M, Ding S, Zoubchenok D, Alsahafi N, Coutu M, Brassard N, Park J, Courter JR, Melillo B et al..  2015.  Small CD4 Mimetics Prevent HIV-1 Uninfected Bystander CD4 + T Cell Killing Mediated by Antibody-dependent Cell-mediated Cytotoxicity.. EBioMedicine. 3:122-34.
Pritchard LK, Vasiljevic S, Ozorowski G, Seabright GE, Cupo A, Ringe R, Kim HJ, Sanders RW, Doores KJ, Burton DR et al..  2015.  Structural Constraints Determine the Glycosylation of HIV-1 Envelope Trimers.. Cell Rep.
Zhou T, Lynch RM, Chen L, Acharya P, Wu X, Doria-Rose NA, M Joyce G, Lingwood D, Soto C, Bailer RT et al..  2015.  Structural Repertoire of HIV-1-Neutralizing Antibodies Targeting the CD4 Supersite in 14 Donors.. Cell. 161(6):1280-92.
Guenaga J, Dubrovskaya V, de Val N, Sharma SK, Carrette B, Ward AB, Wyatt RT.  2015.  Structure-guided redesign increases the propensity of HIV Env to generate highly stable soluble trimers.. J Virol.

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