Publications

Found 404 results
2015
Willis JR, Sapparapu G, Murrell S, Julien J-P, Singh V, King HG, Xia Y, Pickens JA, Labranche CC, Slaughter JC et al..  2015.  Redesigned HIV antibodies exhibit enhanced neutralizing potency and breadth.. J Clin Invest. 125(6):2523-31.
Cubas R, van Grevenynghe J, Wills S, Kardava L, Santich BH, Buckner CM, Muir R, Tardif V, Nichols C, Procopio F et al..  2015.  Reversible Reprogramming of Circulating Memory T Follicular Helper Cell Function during Chronic HIV Infection.. J Immunol. 195(12):5625-36.
Dai K, He L, Khan SN, O'Dell S, McKee K, Tran K, Li Y, Sundling C, Morris CD, Mascola JR et al..  2015.  Rhesus Macaque B-Cell Responses to an HIV-1 Trimer Vaccine Revealed by Unbiased Longitudinal Repertoire Analysis.. MBio. 6(6):e01375-15.
Richard J, Veillette M, Ding S, Zoubchenok D, Alsahafi N, Coutu M, Brassard N, Park J, Courter JR, Melillo B et al..  2015.  Small CD4 Mimetics Prevent HIV-1 Uninfected Bystander CD4 + T Cell Killing Mediated by Antibody-dependent Cell-mediated Cytotoxicity.. EBioMedicine. 3:122-34.
Pritchard LK, Vasiljevic S, Ozorowski G, Seabright GE, Cupo A, Ringe R, Kim HJ, Sanders RW, Doores KJ, Burton DR et al..  2015.  Structural Constraints Determine the Glycosylation of HIV-1 Envelope Trimers.. Cell Rep.
Zhou T, Lynch RM, Chen L, Acharya P, Wu X, Doria-Rose NA, M Joyce G, Lingwood D, Soto C, Bailer RT et al..  2015.  Structural Repertoire of HIV-1-Neutralizing Antibodies Targeting the CD4 Supersite in 14 Donors.. Cell. 161(6):1280-92.
Guenaga J, Dubrovskaya V, de Val N, Sharma SK, Carrette B, Ward AB, Wyatt RT.  2015.  Structure-guided redesign increases the propensity of HIV Env to generate highly stable soluble trimers.. J Virol.
Yamada DH, Elsaesser H, Lux A, Timmerman JM, Morrison SL, de la Torre JCarlos, Nimmerjahn F, Brooks DG.  2015.  Suppression of Fcγ-receptor-mediated antibody effector function during persistent viral infection.. Immunity. 42(2):379-90.
Gitlin AD, Mayer CT, Oliveira TY, Shulman, iv Z, Jones MJK, Koren A, Nussenzweig MC.  2015.  T cell help controls the speed of the cell cycle in germinal center B cells.. Science.
Doores KJ, Kong L, Krumm SA, Le KM, Sok D, Laserson U, Garces F, Poignard P, Wilson IA, Burton DR.  2015.  Two classes of broadly neutralizing antibodies within a single lineage directed to the high-mannose patch of HIV envelope.. J Virol. 89(2):1105-18.
Crooks ET, Tong T, Chakrabarti B, Narayan K, Georgiev IS, Menis S, Huang X, Kulp D, Osawa K, Muranaka J et al..  2015.  Vaccine-Elicited Tier 2 HIV-1 Neutralizing Antibodies Bind to Quaternary Epitopes Involving Glycan-Deficient Patches Proximal to the CD4 Binding Site.. PLoS Pathog. 11(5):e1004932.
Pulendran B.  2015.  The varieties of immunological experience: of pathogens, stress, and dendritic cells.. Annu Rev Immunol. 33:563-606.
Caskey M, Klein F, Lorenzi JCC, Seaman MS, West AP, Buckley N, Kremer G, Nogueira L, Braunschweig M, Scheid JF et al..  2015.  Viraemia suppressed in HIV-1-infected humans by broadly neutralizing antibody 3BNC117.. Nature. 522(7557):487-91.
Guenaga J, de Val N, Tran K, Feng Y, Satchwell K, Ward AB, Wyatt RT.  2015.  Well-ordered trimeric HIV-1 subtype B and C soluble spike mimetics generated by negative selection display native-like properties.. PLoS Pathog. 11(1):e1004570.
2014
Scharf L, Scheid JF, Lee J H, West AP, Chen C, Gao H, Gnanapragasam PNP, Mares R, Seaman MS, Ward AB et al..  2014.  Antibody 8ANC195 reveals a site of broad vulnerability on the HIV-1 envelope spike.. Cell Rep. 7(3):785-95.
Eroshkin AM, Leblanc A, Weekes D, Post K, Li Z, Rajput A, Butera ST, Burton DR, Godzik A.  2014.  bNAber: database of broadly neutralizing HIV antibodies.. Nucleic Acids Res.
Huang J, Kang BH, Pancera M, Lee J H, Tong T, Feng Y, Imamichi H, Georgiev IS, Chuang G-Y, Druz A et al..  2014.  Broad and potent HIV-1 neutralization by a human antibody that binds the gp41-gp120 interface.. Nature. 515(7525):138-42.
Halper-Stromberg A, Lu C-L, Klein F, Horwitz JA, Bournazos S, Nogueira L, Eisenreich TR, Liu C, Gazumyan A, Schaefer U et al..  2014.  Broadly Neutralizing Antibodies and Viral Inducers Decrease Rebound from HIV-1 Latent Reservoirs in Humanized Mice.. Cell.
Bournazos S, Klein F, Pietzsch J, Seaman MS, Nussenzweig MC, Ravetch JV.  2014.  Broadly Neutralizing Anti-HIV-1 Antibodies Require Fc Effector Functions for In Vivo Activity.. Cell. 158(6):1243-53.
Falkowska E, Le KM, Ramos A, Doores KJ, Lee J H, Blattner C, Ramirez A, Derking R, van Gils MJ, Liang C-H et al..  2014.  Broadly Neutralizing HIV Antibodies Define a Glycan-Dependent Epitope on the Prefusion Conformation of gp41 on Cleaved Envelope Trimers.. Immunity. 40(5):657-68.
Guttman M, Garcia NK, Cupo A, Matsui T, Julien J-P, Sanders RW, Wilson IA, Moore JP, Lee KK.  2014.  CD4-induced activation in a soluble HIV-1 Env trimer.. Structure. 22(7):974-84.
Madani N, Princiotto AM, Schön A, LaLonde J, Feng Y, Freire E, Park J, Courter JR, Jones DM, Robinson J et al..  2014.  CD4-mimetic small molecules sensitize human immunodeficiency virus to vaccine-elicited antibodies.. J Virol. 88(12):6542-55.
Gitlin AD, Shulman, iv Z, Nussenzweig MC.  2014.  Clonal selection in the germinal centre by regulated proliferation and hypermutation.. Nature. 509(7502):637-40.
Azoitei ML, Ban YA, Kalyuzhny O, Guenaga J, Schroeter A, Porter J, Wyatt R, Schief WR.  2014.  Computational design of protein antigens that interact with the CDR H3 loop of HIV broadly neutralizing antibody 2F5.. Proteins. 82(10):2770-82.
Gao F, Bonsignori M, Liao H-X, Kumar A, Xia S-M, Lu X, Cai F, Hwang K-K, Song H, Zhou T et al..  2014.  Cooperation of B Cell Lineages in Induction of HIV-1-Broadly Neutralizing Antibodies.. Cell. 158(3):481-91.

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