Andrew Ward

2016
Behrens A-J, Vasiljevic S, Pritchard LK, Harvey DJ, Andev RS, Krumm SA, Struwe WB, Cupo A, Kumar A, Zitzmann N et al..  2016.  Composition and Antigenic Effects of Individual Glycan Sites of a Trimeric HIV-1 Envelope Glycoprotein.. Cell Rep.
Lee J H, Ozorowski G, Ward AB.  2016.  Cryo-EM structure of a native, fully glycosylated, cleaved HIV-1 envelope trimer.. Science. 351(6277):1043-8.
Kong R, Xu K, Zhou T, Acharya P, Lemmin T, Liu K, Ozorowski G, Soto C, Taft JD, Bailer RT et al..  2016.  Fusion peptide of HIV-1 as a site of vulnerability to neutralizing antibody.. Science. 352(6287):828-33.
Steichen JM, Kulp DW, Tokatlian T, Escolano A, Dosenovic P, Stanfield RL, McCoy LE, Ozorowski G, Hu X, Kalyuzhniy O et al..  2016.  HIV Vaccine Design to Target Germline Precursors of Glycan-Dependent Broadly Neutralizing Antibodies.. Immunity.
van Gils MJ, van den Kerkhof TLGM, Ozorowski G, Cottrell CA, Sok D, Pauthner M, Pallesen J, de Val N, Yasmeen A, de Taeye SW et al..  2016.  An HIV-1 antibody from an elite neutralizer implicates the fusion peptide as a site of vulnerability.. Nat Microbiol. 2:16199.
McCoy LE, van Gils MJ, Ozorowski G, Messmer T, Briney B, Voss JE, Kulp DW, Macauley MS, Sok D, Pauthner M et al..  2016.  Holes in the Glycan Shield of the Native HIV Envelope Are a Target of Trimer-Elicited Neutralizing Antibodies.. Cell Rep. 16(9):2327-38.
Bornholdt ZA, Turner HL, Murin CD, Li W, Sok D, Souders CA, Piper AE, Goff A, Shamblin JD, Wollen SE et al..  2016.  Isolation of potent neutralizing antibodies from a survivor of the 2014 Ebola virus outbreak.. Science. 351(6277):1078-83.
Kong L, Ju B, Chen Y, He L, Ren L, Liu J, Hong K, Su B, Wang Z, Ozorowski G et al..  2016.  Key gp120 Glycans Pose Roadblocks to the Rapid Development of VRC01-Class Antibodies in an HIV-1-Infected Chinese Donor.. Immunity. 44(4):939-50.
Bonsignori M, Zhou T, Sheng Z, Chen L, Gao F, M Joyce G, Ozorowski G, Chuang G-Y, Schramm CA, Wiehe K et al..  2016.  Maturation Pathway from Germline to Broad HIV-1 Neutralizer of a CD4-Mimic Antibody.. Cell.
He L, de Val N, Morris CD, Vora N, Thinnes TC, Kong L, Azadnia P, Sok D, Zhou B, Burton DR et al..  2016.  Presenting native-like trimeric HIV-1 antigens with self-assembling nanoparticles.. Nat Commun. 7:12041.
Sok D, Pauthner M, Briney B, Lee J H, Saye-Francisco KL, Hsueh J, Ramos A, Le KM, Jones M, Jardine JG et al..  2016.  A Prominent Site of Antibody Vulnerability on HIV Envelope Incorporates a Motif Associated with CCR5 Binding and Its Camouflaging Glycans.. Immunity. 45(1):31-45.
Klasse PJ, Labranche CC, Ketas TJ, Ozorowski G, Cupo A, Pugach P, Ringe RP, Golabek M, van Gils MJ, Guttman M et al..  2016.  Sequential and Simultaneous Immunization of Rabbits with HIV-1 Envelope Glycoprotein SOSIP.664 Trimers from Clades A, B and C.. PLoS Pathog. 12(9):e1005864.
Briney B, Sok D, Jardine JG, Kulp DW, Skog P, Menis S, Jacak R, Kalyuzhniy O, de Val N, Sesterhenn F et al..  2016.  Tailored Immunogens Direct Affinity Maturation toward HIV Neutralizing Antibodies.. Cell. 166(6):1459-1470.e11.
Feng Y, Tran K, Bale S, Kumar S, Guenaga J, Wilson R, de Val N, Arendt H, DeStefano J, Ward AB et al..  2016.  Thermostability of Well-Ordered HIV Spikes Correlates with the Elicitation of Autologous Tier 2 Neutralizing Antibodies.. PLoS Pathog. 12(8):e1005767.
Kong L, He L, de Val N, Vora N, Morris CD, Azadnia P, Sok D, Zhou B, Burton DR, Ward AB et al..  2016.  Uncleaved prefusion-optimized gp140 trimers derived from analysis of HIV-1 envelope metastability.. Nat Commun. 7:12040.
2015
Garces F, Lee J H, de Val N, de la Peña ATorrents, Kong L, Puchades C, Hua Y, Stanfield RL, Burton DR, Moore JP et al..  2015.  Affinity Maturation of a Potent Family of HIV Antibodies Is Primarily Focused on Accommodating or Avoiding Glycans.. Immunity. 43(6):1053-63.
Lee J H, Leaman DP, Kim AS, de la Peña ATorrents, Sliepen K, Yasmeen A, Derking R, Ramos A, de Taeye SW, Ozorowski G et al..  2015.  Antibodies to a conformational epitope on gp41 neutralize HIV-1 by destabilizing the Env spike.. Nat Commun. 6:8167.
Schiffner T, de Val N, Russell RA, de Taeye SW, de la Peña ATorrents, Ozorowski G, Kim HJ, Nieusma T, Brod F, Cupo A et al..  2015.  Chemical Cross-Linking Stabilizes Native-Like HIV-1 Envelope Glycoprotein Trimer Antigens.. J Virol. 90(2):813-28.
Sharma SKumar, de Val N, Bale S, Guenaga J, Tran K, Feng Y, Dubrovskaya V, Ward AB, Wyatt RT.  2015.  Cleavage-Independent HIV-1 Env Trimers Engineered as Soluble Native Spike Mimetics for Vaccine Design.. Cell Rep.
Derking R, Ozorowski G, Sliepen K, Yasmeen A, Cupo A, Torres JL, Julien J-P, Lee J H, van Montfort T, de Taeye SW et al..  2015.  Comprehensive Antigenic Map of a Cleaved Soluble HIV-1 Envelope Trimer.. PLoS Pathog. 11(3):e1004767.
Julien J-P, Lee J H, Ozorowski G, Hua Y, de la Peña ATorrents, de Taeye SW, Nieusma T, Cupo A, Yasmeen A, Golabek M et al..  2015.  Design and structure of two HIV-1 clade C SOSIP.664 trimers that increase the arsenal of native-like Env immunogens.. Proc Natl Acad Sci U S A.
Sliepen K, van Montfort T, Ozorowski G, Pritchard LK, Crispin M, Ward AB, Sanders RW.  2015.  Engineering and Characterization of a Fluorescent Native-Like HIV-1 Envelope Glycoprotein Trimer.. Biomolecules. 5(4):2919-34.

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